Why use charcoal-stripped FBS?

 

You might have heard about fetal bovine serum for your pet. This is the secret to getting healthy babies! But what is fetal bovine serum, and why use charcoal-stripped FBS?

Charcoal-strippedfetal bovine serum (FBS) is a type of cell culture media supplement widely used in biotechnology and biomedical research. FBS is derived from the blood of fetuses of cows and contains a wide range of nutrients, growth factors, and other bioactive molecules that are important for the growth and proliferation of various types of cells in culture.

 


 

However, FBS can also contain unwanted contaminants, such as hormones, drugs, and viruses that can interfere with experimental results and lead to false positives. Charcoal-stripped FBS is a special type treated with activated charcoal to remove these contaminants, making it a more reliable and consistent source of nutrients for cell culture experiments.

Charcoal stripping is a process used to remove steroids from serum.

 

This technique aims to remove all traces of contaminants from your product while retaining its positive properties. These contaminants can come from various sources, including the animals from which the FBS is collected, the processing and handling of the FBS, and the storage and transportation of the FBS. For example, FBS can contain traces of hormones, such as estrogen and progesterone that may affect the growth and behavior of cells in culture. In addition, FBS can contain residues of drugs and other chemicals that may have been administered to the animals from which the FBS was collected, such as antibiotics and insecticides.

 

 

There are several methods for producing charcoal-stripped FBS, but the most common procedure involves adding activated charcoal and incubating the mixture for some time. The activated charcoal binds to the contaminants in the FBS and removes them through adsorption. The charcoal-stripped FBS is then filtered to remove the charcoal and any remaining contaminants, and the resulting product is sterile and ready for use in cell culture experiments.

 

Despite the benefits of charcoal-stripped FBS, it is important to note that this type of FBS is not completely free of contaminants. While it is generally considered to be a more reliable and consistent source of nutrients for cell culture experiments, it is still possible for trace amounts of contaminants to remain in the FBS after the charcoal treatment. Therefore, it is important for researchers to carefully consider the potential impact of these contaminants on their experiments and to use appropriate controls to ensure the validity of their results.

 

Charcoal stripping removes many unwanted components of serum while retaining its positive properties. 

Charcoal stripping is a process that removes many of the unwanted components of serum while retaining its positive properties.

  • Steroids, proteins and lipids are removed from serum with charcoal stripping.
  • It helps keep cells alive and active in culture or immunology experiments by acting as an osmotic pump against external factors such as high salt concentrations or temperature changes that otherwise kill cells.

Using charcoal-stripped serum can also be beneficial in cell biology research because it helps preserve tissues during tissue cultures by removing damaging chemicals such as phenol derivatives in some biological solutions used during these experiments.

Use charcoal-stripped fetal bovine serum for better results

You can expect better outcomes and quality when you use a charcoal-stripped fetal bovine serum. You will also get higher cell viability and growth rates than other samples.

 

The reason why this happens is because of fact that charcoal-stripped fetal bovine serum contains fewer nuclei than other types of FBS. This means that there are fewer cells in your sample which means they will be easier to culture without causing problems like contamination or toxicity issues with your culture media.

 

In conclusion, charcoal-stripped FBS is a valuable tool for biotechnology and biomedical research researchers. Removing unwanted contaminants helps eliminate false positives and improve the reproducibility of cell culture experiments. While it is not completely free of contaminants, it is generally considered a more reliable and consistent source of nutrients for cells in culture.

If you have questions about charcoal-stripped FBS, feel free to contact us. We’re happy to help!

 


 

 

 



 

 

 


Comments

Post a Comment

Popular posts from this blog

What Is A Bankers Bank?

Image
Everyone knows that banking is a very vast field and they offer various services that people aren't usually aware of. Among them one thing that confuses a lot of people and they ask that what is a bankers bank . It is basically a kind of bank that is created by banks who are large and well established. The reason for the existence of a bankers bank is to be of service to the charters bank that created them. It is important to know that the services of a bankers bank aren't open to the public in any criteria as they are specifically designed to help and support community banks.     Understanding a bankers bank Since the bankers bank is not open to the public in any fashion, they are formed to help and support community banks in competing effectively with larger banking entities. The first bank was opened in 1975 by the name of United Bankers Bank in Bloomington, Minnesota. There are only a handful of bankers banks in the whole nation. Credit unions and bankers bank People...
Read more

How To Secure Home From Theft?

Image
No matter what type of security you want, whether you want protection for your family or protect your home or valuables, hiring a residential security guard are the best decision to make. Hiring a security guard is an excellent way to secure your home from robbery and other forms of burglary. The experienced security guards know strategies to safeguard you and your family against intruders, vandals, burglars, thieves, and other potential threats. The security guards ensure that all your belongings are safe and secure. And you can relax knowing that someone is there to take care.       The crime rate is increasing rapidly due to economic indefincincies and lack of security. Saving your home and area from thieves has become tricky as they dig into your home when you aren’t home. It is interesting to note here that most burglaries occur in the middle of the day. People assume they need to secure their house at night, but this isn’t true because break-ins mostly happe...
Read more

What Are Exosomes For Skin?

Image
Exosomes are small, membrane-bound vesicles secreted by most cell types, including cancer cells. They range in size from 30 to 150 nanometers in diameter and contain various bio-molecules, such as proteins, lipids, RNA, and DNA. Exosomes play a role in intercellular communication, as they can be taken up by other cells and transfer their contents, including genetic material, to recipient cells. This transfer of information can affect a huge range of cellular processes that includes proliferation, differentiation, and immune response. Exosomes have been found to have a role in many physiological and pathological processes, including cancer, inflammation, and neurodegenerative diseases, and are being investigated as potential diagnostic and therapeutic targets. Exosomes are produced by cells through the endocytic pathway. The process begins with forming an early endosome, which then matures into a late endosome that eventually fuses with the cell membrane, releasing the exosome into the...
Read more